Review Articles
139. Deshaies, R.J. (2015). Protein degradation: Prime time for PROTACs. Nat. Chem. Biol. 11, 634-635.
137. Deshaies, R.J. (2014). Proteotoxic crisis, the ubiquitin-proteasone system, and cancer therapy. BMC Biol. 12:94. Journal
135. Deshaies, RJ. Structural biology: Corralling a protein-degradation regulator. (2014). Nature 512, 145-146. Journal
110. Deshaies, R.J., Emberley, E.D., and Saha, A. (2010). Control of cullin-ring ubiquitin ligase activity by Nedd8. Subcell. Biochem. 54, 41-56. Journal
102. Deshaies, R.J. and Joazeiro, C.A.P. (2009). RING domain E3 ubiquitin ligases. Annu. Rev. Biochem. 78, 399-434. PDF
101. Deshaies, R.J. (2009). Drug discovery: Fresh target for cancer therapy (News & Views). Nature 458, 709-710. PDF
85. Petroski, M.D. and Deshaies, R.J. (2005). In vitro reconstitution of SCF substrate ubiquitination with purified proteins. Method. Enzymol. 398, 143-158. PDF
84. Verma, R. and Deshaies, R.J. (2005). Assaying degradation and deubiquitination of a ubiquitinated substrate by purified 26S proteasomes. Method. Enzymol. 398, 391-399. PDF
83. Mayor, T. and Deshaies, R.J. (2005). Two-step affinity purification of multiubiquitylated proteins from Saccharomyces cerevisiae. Method. Enzymol. 399, 385-392. PDF
79. Petroski, M.D. and Deshaies, R. J. (2005). Function and regulation of cullin-RING ubiquitin ligases. Nat. Rev. Mol. Cell. Biol. 6, 9-20. PDF
69. Lipford, J.R., and Deshaies, R.J. (2003). Diverse roles for ubiquitin-dependent proteolysis in transcriptional activation. Nat. Cell Biol. 5, 845-50. PDF
68. Cope, G.A., and Deshaies, R.J. (2003). COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases. Cell 114, 663-71. Journal
67. Petroski, M.D, and Deshaies, R.J. (2003). Redundant degrons ensure the rapid destruction of sic1 at the g1 /s transition of the budding yeast cell cycle. Cell Cycle 2, 410-1. Journal
58. Deshaies, R.J., Seol, J.H., McDonald, W.H., Cope, G., Lyapina, S.,Shevchenko, A., Shevchenko A., Verma, R., and Yates, J.R. (2002). Charting the protein complexome in yeast by mass spectrometry. Mol. Cell. Prot. 1, 3-10. Journal
57. Deshaies, R.J. and Ferrell, J.E. (2001). Multisite phosphorylation and the countdown to S phase. Cell 107, 819-822. Journal
56. Deshaies, R.J., and Eilers, M. (2001). Editorial Review: Cell Multiplication. Curr. Opin. Cell Biol. 13, 729-730. PDF
38. Deshaies, R.J., and Meyerowitz, E.M. (2000). COP1 patrols the night beat. Nat. Cell Biol. 2, E102-E104. Journal
37. Verma, R., and Deshaies, R.J. (2000). A proteasome howdunit: the case of the missing signal. Cell 101, 341-344. Journal
36. Deshaies, R.J. (1999). SCF and cullin/RING H2-based ubiquitin ligases. Annu. Rev. Cell Dev. Biol. 15, 435-467. Journal
30. Peters, J.-M., King, R.W., and Deshaies, R.J. (1998). Cell cycle control by ubiquitin-dependent proteolysis. In Ubiquitin and the Biology of the Cell (Ed. J.-M. Peters et al.) Plenum Press, NY. PDF
23. Deshaies, R.J. (1997). Phosphorylation and proteolysis: partners in the regulation of cell division in budding yeast. Curr. Opin. Genet. Dev. Biol. 7, 7-16. PDF
22. King, R.W., Deshaies, R.J., Peters, J.M., and Kirschner, M.W. (1996). How proteolysis drives the cell cycle. Science 274, 1652-1659. PDF
21. Deshaies, R.J. (1995). The self-destructive personality of a cell cycle in transition. Curr. Opin. Cell Biol. 7, 781-789. PDF
20. Deshaies, R.J. (1995). Make it or break it: the role of ubiquitin-dependent proteolysis in cellular regulation. Trends Cell Bio. 5, 428-434. PDF
137. Deshaies, R.J. (2014). Proteotoxic crisis, the ubiquitin-proteasone system, and cancer therapy. BMC Biol. 12:94. Journal
135. Deshaies, RJ. Structural biology: Corralling a protein-degradation regulator. (2014). Nature 512, 145-146. Journal
110. Deshaies, R.J., Emberley, E.D., and Saha, A. (2010). Control of cullin-ring ubiquitin ligase activity by Nedd8. Subcell. Biochem. 54, 41-56. Journal
102. Deshaies, R.J. and Joazeiro, C.A.P. (2009). RING domain E3 ubiquitin ligases. Annu. Rev. Biochem. 78, 399-434. PDF
101. Deshaies, R.J. (2009). Drug discovery: Fresh target for cancer therapy (News & Views). Nature 458, 709-710. PDF
85. Petroski, M.D. and Deshaies, R.J. (2005). In vitro reconstitution of SCF substrate ubiquitination with purified proteins. Method. Enzymol. 398, 143-158. PDF
84. Verma, R. and Deshaies, R.J. (2005). Assaying degradation and deubiquitination of a ubiquitinated substrate by purified 26S proteasomes. Method. Enzymol. 398, 391-399. PDF
83. Mayor, T. and Deshaies, R.J. (2005). Two-step affinity purification of multiubiquitylated proteins from Saccharomyces cerevisiae. Method. Enzymol. 399, 385-392. PDF
79. Petroski, M.D. and Deshaies, R. J. (2005). Function and regulation of cullin-RING ubiquitin ligases. Nat. Rev. Mol. Cell. Biol. 6, 9-20. PDF
69. Lipford, J.R., and Deshaies, R.J. (2003). Diverse roles for ubiquitin-dependent proteolysis in transcriptional activation. Nat. Cell Biol. 5, 845-50. PDF
68. Cope, G.A., and Deshaies, R.J. (2003). COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases. Cell 114, 663-71. Journal
67. Petroski, M.D, and Deshaies, R.J. (2003). Redundant degrons ensure the rapid destruction of sic1 at the g1 /s transition of the budding yeast cell cycle. Cell Cycle 2, 410-1. Journal
58. Deshaies, R.J., Seol, J.H., McDonald, W.H., Cope, G., Lyapina, S.,Shevchenko, A., Shevchenko A., Verma, R., and Yates, J.R. (2002). Charting the protein complexome in yeast by mass spectrometry. Mol. Cell. Prot. 1, 3-10. Journal
57. Deshaies, R.J. and Ferrell, J.E. (2001). Multisite phosphorylation and the countdown to S phase. Cell 107, 819-822. Journal
56. Deshaies, R.J., and Eilers, M. (2001). Editorial Review: Cell Multiplication. Curr. Opin. Cell Biol. 13, 729-730. PDF
38. Deshaies, R.J., and Meyerowitz, E.M. (2000). COP1 patrols the night beat. Nat. Cell Biol. 2, E102-E104. Journal
37. Verma, R., and Deshaies, R.J. (2000). A proteasome howdunit: the case of the missing signal. Cell 101, 341-344. Journal
36. Deshaies, R.J. (1999). SCF and cullin/RING H2-based ubiquitin ligases. Annu. Rev. Cell Dev. Biol. 15, 435-467. Journal
30. Peters, J.-M., King, R.W., and Deshaies, R.J. (1998). Cell cycle control by ubiquitin-dependent proteolysis. In Ubiquitin and the Biology of the Cell (Ed. J.-M. Peters et al.) Plenum Press, NY. PDF
23. Deshaies, R.J. (1997). Phosphorylation and proteolysis: partners in the regulation of cell division in budding yeast. Curr. Opin. Genet. Dev. Biol. 7, 7-16. PDF
22. King, R.W., Deshaies, R.J., Peters, J.M., and Kirschner, M.W. (1996). How proteolysis drives the cell cycle. Science 274, 1652-1659. PDF
21. Deshaies, R.J. (1995). The self-destructive personality of a cell cycle in transition. Curr. Opin. Cell Biol. 7, 781-789. PDF
20. Deshaies, R.J. (1995). Make it or break it: the role of ubiquitin-dependent proteolysis in cellular regulation. Trends Cell Bio. 5, 428-434. PDF